Priv. Doz. Dr. Regina Fluhrer

Curriculum Vitae

PD Dr. Regina Fluhrer studied food chemistry at the Ludwig-Maximilians Universität (LMU) and at the Technical University in Munich (TUM). For her Ph.D. studies (2000 – 2003) she joined the laboratory of Christian Haass and intensively worked on the catalytic specificities of BACE-1 (β-site APP cleaving enzyme) and BACE-2. BACE-1 is one of the key players involved in the generation of the Amyloid-β-peptide (Aβ) and a major factor in the development of Alzheimer’s disease. During her time as a posdoctoral fellow (2003-2005) Dr. Fluhrer became more and more interested in intramembrane proteases and was able to show that γ-secretase, the other key player involved in the generation of the Amyloid-β-peptide (Aβ), has an additional function in apoptosis.

Since 2005 Dr. Fluhrer has a permanent position at the institute of Prof. Haass. In 2006 she took over responsibility for the subjects of biochemistry and molecular biology for medical students and coordinates the teaching duties for the whole institute. Since that time her research focuses on regulated intramembrane proteolysis. Also in 2006 she received the Böhringer Ingelheim APOPIS award for young researchers for her studies on proteolytic mechanisms involved in Alzheimer’s disease. In 2008 Dr. Fluhrer finished her “Habilitation” and since 2009 she is university lecturer (Privatdozentin) at the medical faculty of the LMU Munich. Within the DZNE Dr. Fluhrer will coordinate all administrative issues in Munich and analyze potential side effects of newly developed γ-secretase inhibitors.